ACTA Oral Biochemistry

Oral Biochemistry

 

 

Research at the Department of Oral Biochemistry is directed to understand the mech­­anisms by which defensive systems in saliva maintain oral health on a molec­ular level. Such knowledge expands the ability to modulate natural defence in oral dis­eases, specifically in areas of salivary defence factors. Because the oral cavity functions as portal to the gastro-intestinal and respiratory tracts, defensive systems in saliva are not only relevant for the maintenance of oral health but for the entire organism as well.

Areas of Expertise

Saliva and salivary diagnostics

​

Peptide synthesis

​

Wound healing

​

Protective coatings

 

Customised research

​

 

​

​​​​​​​​​

Research at ACTA

 

 

​In general, research ACTA focuses on the physiology and pathology of the tissues in and around the oral cavity. For more information please visit www.acta.nl

Recent Publications

Sphingoid Bases Inhibit Acid-Induced Demineralization of Hydroxyapatite.

Valentijn-Benz et al. Caries Res. 2014 Oct 9;49(1):9-17.

 

Complement activation by salivary agglutinin is secretor status dependent.

Gunput et al. Biol Chem. 2014 Jul 24.

 

Tailor made plasmin substrates as potential diagnostic tool to test for mastitis.

Bikker et al. Vet Res Commun. 2014 Jul 6.

 

Membrane-active mechanism of LFchimera against B. pseudomallei and B. thailandensis.

Kanthawong et al. Biometals. 2014 Oct;27(5):949-56.

 

Saliva and wound healing.

Brand et al. Monogr Oral Sci. 2014;24:52-60.